Scientist I/II, Immunotherapy

Cambridge, MA

Characterization of Gene Modified T Cells 

Join bluebird bio’s enthusiastic and collaborative Cellular Immunotherapy team by contributing to the overall success of our novel gene-based immunotherapy approach. This new Scientist will join our group to design, develop and evaluate novel cellular immunotherapy approaches for clinical applications. 

About the job:

  • Work in a team focused on preclinical development of cellular therapeutics
  • Design and develop immunological assays to characterize genetically engineered primary T cells
  • Potential to lead a team of 1-2 research associates
  • Coordinate research projects evaluating strategies to improve efficacy of cellular therapeutics
  • Prepare all technical reports needed in support of an exploratory project moving to process development
  • Exercise independent judgment in development of new methods, techniques and evaluation criteria
  • Effectively interface with other scientific groups in bluebird bio to facilitate the success of projects

About you:

  • PhD in molecular or cellular immunology
  • 2+ years’ experience beyond PhD as a post-doc in immunology or tumor biology
  • Applied experience in T cell or other immunotherapies
  • Ability to independently design, execute, interpret and communicate experimental results
  • Experience with innovative assay development to assess novel biology
  • Expertise in mammalian cell culture, with specific experience isolating and propagating in vitro culture of human/mouse T lymphocytes
  • Experienced with flow cytometry of primary human cells – cell sorting experience a plus
  • Experienced with immunological assays to assess T cell function
  • Expertise in signaling, innate immunity and cytokine function preferred
  • Expertise in gene editing a plus
  • Experience in working in animal models of adoptive immunotherapy for autoimmune disease or Oncology
  • Proven ability to effectively organize experiments to prosecute research projects studying T cell therapeutics
  • Proven ability to effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines
  • Ability to work as part of a team, collaborating with members of other functional groups
  • Understanding of safe lab practices and BSL requirements
  • Excellent computer skills and experience with Microsoft Excel. Prism, sequence analysis, Flow cytometry data analysis software experience essential
  • “do-what-it-takes” attitude
  • Independently motivated, detail oriented and good problem solving ability
  • Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
  • Be ready to embrace the principles of the bluebird bio culture:  b colorful, b cooperative, and b yourself
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